化学
串联
电化学
组合化学
有机化学
电极
物理化学
复合材料
材料科学
作者
Yunfei Tian,Luping Zheng,Yu-Ting Yang,Jiayi Liu,Zhaoxia Jing,Zejiang Li,Weijun Fu
标识
DOI:10.1002/adsc.202300205
摘要
An electrochemical oxydifluoroethylation of alkenes involving the anodic oxidative generation of MeCF2 radical has been achieved, which enabled to construct diversified difluoroethylated benzoxazines and lactones in 35–87% yields. Moreover, the developed protocol was also extended to the synthesis of cyclopropyldifluoromethylated benzoxazines. Detailed mechanistic studies indicated the reaction underwent a radical process concerned with tandem C−CF2R and C−O bond formation.
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