A Cascade Markovnikov Addition / Lewis Acid-Catalyzed Rearrangement of Methyleneaziridines and Carboxylic Acids: Continuous-Flow Synthesis of α-Amidoketones

α-Amidoketones are essential structural motifs in pharmaceuticals and synthetic chemistry. In this study, we describe a novel synthetic method that involves a cascade addition reaction, followed by a Lewis acid-catalyzed...