生物
环节动物
幼虫
变形
双侧
附属物
进化生物学
动物
后口
解剖
脊椎动物
生态学
系统发育学
遗传学
基因
作者
Francisco M Martin-Zamora,Yan Liang,Kero Guynes,Allan Carrillo-Baltodano,Billie E. Davies,Rory D. Donnellan,Yongkai Tan,Giacomo Moggioli,Océane Seudre,Martin T. Tran,Kate Mortimer,Nicholas M. Luscombe,Andreas Hejnol,Ferdinand Marlétaz,José M. Martín-Durán
出处
期刊:Nature
[Springer Nature]
日期:2023-01-25
卷期号:615 (7950): 105-110
被引量:5
标识
DOI:10.1038/s41586-022-05636-7
摘要
Indirect development with an intermediate larva exists in all major animal lineages1, which makes larvae central to most scenarios of animal evolution2-11. Yet how larvae evolved remains disputed. Here we show that temporal shifts (that is, heterochronies) in trunk formation underpin the diversification of larvae and bilaterian life cycles. We performed chromosome-scale genome sequencing in the annelid Owenia fusiformis with transcriptomic and epigenomic profiling during the life cycles of this and two other annelids. We found that trunk development is deferred to pre-metamorphic stages in the feeding larva of O. fusiformis but starts after gastrulation in the non-feeding larva with gradual metamorphosis of Capitella teleta and the direct developing embryo of Dimorphilus gyrociliatus. Accordingly, the embryos of O. fusiformis develop first into an enlarged anterior domain that forms larval tissues and the adult head12. Notably, this also occurs in the so-called 'head larvae' of other bilaterians13-17, with which the O. fusiformis larva shows extensive transcriptomic similarities. Together, our findings suggest that the temporal decoupling of head and trunk formation, as maximally observed in head larvae, facilitated larval evolution in Bilateria. This diverges from prevailing scenarios that propose either co-option9,10 or innovation11 of gene regulatory programmes to explain larva and adult origins.
科研通智能强力驱动
Strongly Powered by AbleSci AI