锰
钴
基因敲除
镍
锂(药物)
神经毒性
化学
活性氧
毒理
DNA损伤
氧化磷酸化
药理学
锂钴氧化物
氧化应激
氧化还原
线粒体
氧气
氧化物
氧化损伤
生殖毒性
无机化学
代谢物
碱性电池
生物物理学
毒性
生物化学
作者
Roi Faroud Lopez,Javier Huayta,Gordon D. Z. Williams,Sarah A. Seay,Pooja Lalwani,Sasha Bacot,Avner Vengosh,Joel N. Meyer
出处
期刊:Environmental science
[Royal Society of Chemistry]
日期:2025-01-01
卷期号:4 (11): 1767-1781
被引量:5
摘要
altered several parameters, knockdown of these genes did not increase or decrease the effects of LiNMCs. However, we did find that exposure to LiNMC caused degeneration of dopaminergic, cholinergic, glutamatergic, and GABAergic neurons, but not serotonergic neurons or glial cells. Interestingly, it appears that the developmental neurotoxicity was driven either by a particle-specific effect, or a component other than lithium, because exposure to lithium chloride at the same concentration had no effect.
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