Plasmonic nanopore array to detect translocating DNA and proteins at single molecule level by Raman Spectroscopy

Plasmonic nanopores are emerging as powerful sensing devices since they provide an additional optical sensing modality to the typical electrical readout obtained from solid-state nanopores. In particular, the Raman fingerprint of translocating molecules obtained by Surface Enhanced Raman Spectroscopy contain unique information on the chemical constituents. Here, we report on a functionalized plasmonic nanopore array to perform flow-through sensing of λ-DNA molecules. We acknowledge support from Horizon 2020 (ProID GA 964363).