Redefining the Gastric Microbes in Promoting Gastric Tumorigenesis: The Rise of the Non–H. pylori Microbiome

Summary: Gastric cancer remains one of the top cancers in China compared with Western countries, mainly attributed to the high rates of Helicobacter pylori infection. However, recent discoveries on the non–H. pylori gastric microbiome have led to a paradigm shift in our understanding of microbial risk factors driving gastric cancer, which will impact future screening and prevention strategies.