Treatment of diffuse axonal injury in severe head injury

Objective: To investigate the diagnosis and treatment of diffuse axonal injury(DAI) in severe head injury.Methods: Clinical data of 34 patients with diffuse axonal injury in severe head injury were studied retrospectively.Results: Of the 34 patients with DAI,26cases survived(76.47%),among them,good recovery and moderate disability(47.06%) in16 cases,severe disability and persistent vegetative state(PVS) in 10 cases(29.41%);8 cases died(23.53%).Conclusion: Diffuse axonal injury is the severest condition of the severe head injury;it usually has very high incidence of disability and mortality.Systemic and comprehensive treatment taken to manage primary injury and secondary brain injury is critical to enhance curative rate,reduce disability and mortality.