Research Progress on Pentose Metabolic Engineered Corynebacterium glutamicum

To improve the economic benefits of lignocellulosic biorefinery with Corynebacterium glutamicum,one of the critical pathway is to efficiently utilize pentose from hemicellulose.Corynebacterium glutamicum is widely used in amino acid and nucleotide industrial production.It can produce significant amount of amino acids even at steady phase,and can withstand growth inhibitors like furfurals,5-hydroxymethylfurfural,which make it more suitable as a potent lignocellulose catalytic conversion biocatalyst.Research progress and strategy about xylose and arabinose utilizing genetic engineering C.glutamicum construction is reviewed,and the future research direction on optimization of pentose metabolic capabilities are also proposed.