Comparison of polysaccharide iron complexes used as iron supplements

An oral hematinic marketed as “water soluble polysaccharide iron complex” (Vitaline Formulas) has been characterized using x-ray powder diffraction and Mössbauer spectroscopy. Another polysaccharide iron complex marketed as Niferex (Central Pharmaceuticals) has been previously studied by us and found to have a core similar to similar to ferrihydrite, but with some long-range order of the mineral akaganéite, β-FeOOH. The latter is seen in other ferric carbohydrate complexes synthesized by the hydrolysis of FeCl3. This commercial product, however, is very different and has a mixture of iron components including hematite (α-Fe2O3) magnetite (Fe3O4), geothite (α-FeOOH), iron metal, and a ferrous salt.