The relation between bridgehead reactivity and electronic effects

Electronic effects on bridgehead reactivity examined by means of UV/VIS and NMR spectroscopic methods lead to the conclusion that bridgehead reactivity is influenced both by angle strain and by electronic effects. In most cases both effects influence the reactivity in the same direction. Electronic effects are especially important when only a small change in bridgehead bond angles occurs during the reaction. This is given in highly strained bridgehead systems.