Why we need to implement intramolecular hydrogen-bonding considerations in drug discovery

Future Medicinal ChemistryVol. 9, No. 1 CommentaryWhy we need to implement intramolecular hydrogen-bonding considerations in drug discoveryGiulia Caron & Giuseppe ErmondiGiulia Caron*Author for correspondence: E-mail Address: giulia.caron@unito.it Department of Molecular Biotechnology & Health Sciences, University of Torino, Via Quarello, 15, 10135-Torino, ItalySearch for more papers by this author & Giuseppe Ermondi Department of Molecular Biotechnology & Health Sciences, University of Torino, Via Quarello, 15, 10135-Torino, ItalySearch for more papers by this authorPublished Online:13 Dec 2016https://doi.org/10.4155/fmc-2016-0195AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareShare onFacebookTwitterLinkedInReddit View articleKeywords: ADME-Toxdrug designdrug discoveryintramolecular hydrogen bondintramolecular hydrogen bond propensityReferences1 Castellano R. Special issue: intramolecular hydrogen bonding. 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