Clinical and immunological analysis of extrarenal lupus activity in lupus nephritis patients after end stage renal disease

Objective To investigate the evaluation of extrarenal activity in lupus nephritis patients with end stage renal disease (ESRD).Methods 69 patients who received maintenance dialysis at the Second Affiliated Hospital of Lanzhou Medical College from 1990～1998 were studied retrospectively. Results 24 patients (35%) had clinical lupus activity before dialysis. But during the first year of dialysis, 39 patients (57%) experienced lupus activity, and decreased for years thereafter (P0.05).serologic abnormalities improved gradually over time (P0.05). Conclusions Extrarenal lupus activity in lupus nephritis after ESRD is not common, especially during the first year of dialysis,which can be relieved by using of short -term coticoid.