Advance in Aptamer-based Biosensors

As antibody's substitute,aptamer has wide perspective on veterinary drugs detection,clinic diagnose,targeted therapy.Aptamer-based biosensers had been prepared with aptamers binding to biosensors.The concept of aptamer,its advantages,and principle,detectability,application of the different aptamer-based biosensors,which are fluorescence biosensors,electrochemical biosensors,colorimetric sensors,SERS biosensors and SPR biosensors were summarized.The perspective of aptamer-based biosensors were reviewed on detection of veterinary drug residue,and diagnosis of animal diseases.