Objective:To study the effect of sedative and hypnotic of Spina Date Seed extract on mice.Methods:Through direct sleep experiment,experiment and to extend the disappointment behavior observation of pentobarbital sodium mice sleep time experimental investigation Spina Date Seed extract on mice sedative and hypnotic effects.Results: Spina Date Seed extract on mice directly sleep function is weak,Date Seed extract enable mice activity decreases,extend sodium pentobarbital mice sleep time.Conclusions: Spina Date Seed extract have the effects of sedative and hypnotic.