A novel phenolic glycoside from Cibotium barometz

Objective To study the chemical constituents from Cibotium barometz continuously.Methods Column chromatography and HPLC were carried out to isolate and purify the chemical compounds in the ethanol extract from C.barometz,and their structures were elucidated on the basis of spectroscopy.Results Six compounds isolated from C.barometz were identified as 6-O-protocatechuoyl-D-glucopyranose(1),3-O-caffeoyl-D-glucopyranose(2),1-O-caffeoyl-β-D-glucopyranose(3),caffeic acid(4),protocatechuic acid(5),and p-hydroxybenzoic acid(6).Conclusion Compounds 1—3 and 6 are isolated from C.barometz for the first time,and compound 1 is a novel penolic glucoside named cibotiumbaroside D.