New economic growth theory and new trade theory are considered that knowledge outflow and economic growth are linked closely.Base on the factors research which influences the knowledge spillover effect at home and abroad,the paper divides the influence factors into internal and external factors.Internal factors mean the subject and object of knowledge spillover effect itself,while the external is the factors except subject and object of knowledge spillover effect itself.Their functions constitute the external environment of knowledge spillover effects taking some economic function to analysis these factors.