Screening of Protein Interacting with HEV by Yeast Two-hybrid from Human Leucocyte cDNA Library

Using yeast two-hybrid system to screen the protein interacting with HEV from human leucocyte cDNA library,four clones interacting with apoptin were identified.One of them was P38IP(aa510-733).Cell co-immunoprecipitation showed that E2 could bind to P38IP in mammalian cells.