As populations and water demand increase, more sustainable water sources are needed. Wastewater reuse is a major opportunity. Treated wastewater is available for non-potable applications and drinking water production. Direct potable reuse and planned indirect potable reuse provide sustainable drinking water; other reuse applications can offset current drinking water uses at lower cost due to lower end-use quality requirements. There is some public reluctance to choose potable reuse, but planned reuse projects provide drinking water of higher quality than typical natural sources. Guidance is available to assure safe and high-quality reused water.