来那度胺
骨髓增生异常综合症
多发性骨髓瘤
癌症研究
生物
肿瘤科
医学
免疫学
骨髓
作者
Virginie Chesnais,Aline Renneville,Andréa Toma,Jérôme Lambert,Marie Passet,Florent Dumont,Sylvie Chevret,Julie Lejeune,Anna Raimbault,Aspasia Stamatoullas,Christian Rosé,Odile Beyne‐Rauzy,Jacques Delaunay,Éric Solary,Pierre Fenaux,François Dreyfus,Claude Preudhomme,Olivier Kosmider,Michaëla Fontenay
出处
期刊:Blood
[Elsevier BV]
日期:2015-12-02
卷期号:127 (6): 749-760
被引量:39
标识
DOI:10.1182/blood-2015-04-640128
摘要
Key Points Lenalidomide treatment has variable transient effects on the clonal architecture of myelodysplastic syndromes without 5q deletion. Lenalidomide is unlikely to eradicate myelodysplastic clones characterized by combinations of SF3B1, TET2, DNMT3A, and ASXL1 mutations.
科研通智能强力驱动
Strongly Powered by AbleSci AI