白藜芦醇
化学
阿布茨
DPPH
抗氧化剂
植保素
酚类
激进的
亚胺
有机化学
生物化学
催化作用
作者
Peter Kotora,F. Šeršeň,Juraj Filo,Dušan Loos,Juraj Gregáň,Fridrich Gregáň
出处
期刊:Molecules
[MDPI AG]
日期:2016-01-21
卷期号:21 (1): 127-127
被引量:45
标识
DOI:10.3390/molecules21010127
摘要
Resveratrol (3,5,4'-trihydroxystilbene) is a phytoalexin produced by plants. Resveratrol is known for its anti-cancer, antiviral and antioxidant properties. We prepared imine analogs of resveratrol ((hydroxyphenyliminomethyl)phenols) and tested their antioxidant activity. All prepared resveratrol analogs were able to scavenge 2,2-diphenyl-1-picrylhydrazyl (DPPH), galvinoxyl radical (GOR) and 2,2'-azino-bis(3-ethylbenzothiazoline)-6-sulphonic acid (ABTS) radicals. The antioxidant activity efficiency correlated with the number and position of hydroxyl groups. The most effective antioxidants were resveratrol analogs containing three hydroxyl groups in the benzylidene part of their molecules. These results provide new insights into the relationship between the chemical structure and biological activity of resveratrol analogs.
科研通智能强力驱动
Strongly Powered by AbleSci AI