溃疡性结肠炎
医学
3d打印
炎症性肠病
个性化医疗
3D打印
药剂学
疾病
生物信息学
内科学
药理学
生物医学工程
工程类
机械工程
生物
作者
Yachana Mishra,Vijay Mishra,Alaa A. A. Aljabali,Mohamed El‐Tanani,Gowhar A. Naikoo,Nitin Charbe,Sai Raghuveer Chava,Murtaza M. Tambuwala
出处
期刊:Current Drug Delivery
[Bentham Science]
日期:2023-09-15
卷期号:21
标识
DOI:10.2174/1567201821666230915150544
摘要
Ulcerative colitis (UC) and Crohn's disease (CD) are two types of idiopathic inflammatory bowel disease (IBD) that are increasing in frequency and incidence worldwide, particularly in highly industrialized countries. Conventional tablets struggle to effectively deliver anti-inflammatory drugs since the inflammation is localized in different areas of the colon in each patient. The goal of 3D printing technology in pharmaceutics is to create personalized drug delivery systems (DDS) that are tailored to each individual's specific needs. This review provides an overview of existing 3D printing processes, with a focus on extrusion-based technologies, which have received the most attention. Personalized pharmaceutical products offer numerous benefits to patients worldwide, and 3D printing technology is becoming more affordable every day. Custom manufacturing of 3D printed tablets provides innovative ideas for developing a tailored colon DDS. In the future, 3D printing could be used to manufacture personalized tablets for UC patients based on the location of inflammation in the colon, resulting in improved therapeutic outcomes and a better quality of life.
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