嵌合抗原受体
制造工艺
制造工程
过程（计算）
载体（分子生物学）
业务
计算机科学
免疫疗法
基因
工程类
癌症
医学
化学
材料科学
生物化学
操作系统
内科学
复合材料
重组DNA
作者
Minsoo Khang,Smruthi Suryaprakash,Megan Kotrappa,Widya Mulyasasmita,Shana Topp,John Y. Wu
标识
DOI：10.1016/j.tibtech.2023.04.006
摘要
Chimeric antigen receptor T cells (CAR-T) have demonstrated their potential to revolutionize cancer treatment. However, manufacturing remains a challenge. Multiple manufacturing innovations [e.g., vector and gene engineering, process improvements, hardware innovation, digital innovation, and point-of-care (POC) manufacturing] have the potential to help realize the full potential of CAR-T therapies.
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