细菌性阴道病
生物
微生物群
阴道
乳酸菌
怀孕
滴虫病
生殖健康
生理学
阴道加德纳菌
免疫学
微生物学
医学
妇科
生物信息学
环境卫生
细菌
人口
遗传学
作者
Chitrakshi Chopra,Indu Bhushan,Malvika Mehta,Tanvi Koushal,Amita Gupta,Sarika Sharma,Manoj Kumar,Souhaila Al Khodor,Sandeep Sharma
出处
期刊:Future Microbiology
[Future Medicine]
日期:2022-12-01
卷期号:17 (18): 1501-1513
被引量:17
标识
DOI:10.2217/fmb-2022-0112
摘要
The microbial communities are an indispensable part of the human defense system and coexist with humans as symbionts, contributing to the metabolic functions and immune defense against pathogens. An ecologically stable vaginal microbiota is dominated by Lactobacillus species, which plays an important role in the prevention of genital infections by controlling the vaginal pH, reducing glycogen to lactic acid, and stimulating bacteriocins and hydrogen peroxide. In contrast, an abnormal vaginal microbial composition is associated with an increased risk of bacterial vaginosis, trichomoniasis, sexually transmitted diseases, preterm labor and other birth defects. This microbial diversity is affected by race, ethnicity, pregnancy, hormonal changes, sexual activities, hygiene practices and other conditions. In the present review, we discuss the changes in the microbial community of the vaginal region at different stages of a female's life cycle and its influence on her reproductive health and pathological conditions.
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