自愈水凝胶
纳米纤维素
材料科学
纳米技术
阳极
阴极
药物输送
电极
化学
化学工程
高分子化学
工程类
纤维素
物理化学
作者
Yaqi Zhang,Jingyi Qi,Han Fan,Pu Chen,Borui Li,Ling Zhao,Zikui Bai,Ruquan Zhang,Yue Tao
出处
期刊:ACS applied polymer materials
[American Chemical Society]
日期:2022-11-11
卷期号:4 (12): 9206-9220
被引量:5
标识
DOI:10.1021/acsapm.2c01506
摘要
Self-powered electrically responsive and wearable/implantable drug delivery based on conductive, injectable, and biocompatible hydrogels has emerged as a paradigm for on-demand treatment of diseases. Herein, an electroactive aniline tetramer (AT)-grafted mushroom hyperbranched polysaccharide (TM3a) was codissolved with xanthan gum (XG) and cross-linked with sodium trimetaphosphate (STMP) to fabricate conductive and injectable XG-TMAT-STMP hydrogels. The XG3-TMAT30-STMP hydrogel swollen in a simulated gastric fluid possessed a high conductivity of 23.27 ± 0.20 mS/cm. When applying a potential of 3 V, the apparent diffusion coefficient increased regardless of whether placing DXMS-loaded hydrogels between two electrodes or setting them at the anode or the cathode, indicating electrically responsive release. The extruded XG3-TMAT-STMP hydrogel fibers exhibited good conductivity and stretchablility with low a gauge factor of 1.13 (10% < ε < 50%), suggesting potential applications as bioelectrodes and wearable/implantable drug carriers. Additionally, a triboelectric nanogenerator was fabricated by applying the XG3-TMAT30-STMP hydrogel as a triboelectric material to harvest an output potential of 0.9–1.3 V, indicating feasible application as a self-powered source.
科研通智能强力驱动
Strongly Powered by AbleSci AI