医学
性功能
随机对照试验
国际前列腺症状评分
泌尿系统
前列腺
外科
泌尿科
下尿路症状
内科学
癌症
作者
Luca Cindolo,Davide Campobasso,Enrico Conti,Francesco Uricchio,Francesco Franzoso,Daniele Maruzzi,Lorenzo Viola,Francesco Varvello,Raffaele Balsamo,Giovanni Ferrari,Simone Morselli,Giampaolo Siena
出处
期刊:Journal of Endourology
[Mary Ann Liebert]
日期:2023-03-01
卷期号:37 (3): 323-329
被引量:5
标识
DOI:10.1089/end.2022.0637
摘要
Introduction: Water vapor intraprostatic injection (Rezum procedure) for benign prostatic hyperplasia (BPH) is one of the most promising minimally invasive surgical treatments. Five-year outcomes from the multicenter randomized controlled trial (RCT) demonstrated significant and durable urinary and sexual function results in selected patients. We compared the sexual and urinary outcomes of this procedure in patients satisfying inclusion criteria of the RCT with unselected patients. Materials and Methods: We prospectively followed all patients with symptomatic BPH who underwent Rezum therapy at eight institutions and analyzed the functional results. Patients were divided into two groups: patients who matched the 5-year RCT inclusion criteria (Group A) and patients who did not (Group B). The pre- and postoperative data, complications, presence of antegrade ejaculation, and urinary and sexual outcomes were periodically recorded. Results: A total of 426 patients were eligible for the study (232 in Group A and 194 in Group B). Patients in Group B had a higher American Society of Anesthesiologists score, prostate volume, and postvoid residual measurement. No difference was found in terms of preoperative International Prostate Symptom Score, International Index of Erectile Function, maximum urinary flow, and prostate-specific antigen. Longer operative time and higher number of vapor injections were required in Group B, with no differences in hospital stay, injection density, and complication rates. All the urinary and sexual outcomes improved with no differences between the two groups. The reintervention rate at the latest follow-up visit was 2.6% in Group A and 3.1% in Group B. Conclusions: In our large multicenter series, water vapor intraprostatic injections showed a safe and effective profile regardless of the prostate size, presence of indwelling catheter, antiplatelet/anticoagulant medications, and patients' comorbidities.
科研通智能强力驱动
Strongly Powered by AbleSci AI