自愈水凝胶
一氧化氮
纳米技术
组织工程
材料科学
生物医学工程
化学
医学
有机化学
高分子化学
作者
Lori M. Estes Bright,Yi Wu,Elizabeth J. Brisbois,Hitesh Handa
标识
DOI:10.1016/j.cocis.2023.101704
摘要
Hydrogels provide a plethora of advantages to biomedical treatments due to their highly hydrophilic nature and tissue-like mechanical properties. Additionally, the numerous and widespread endogenous roles of nitric oxide have led to an eruption in research developing biomimetic solutions to the many challenges the biomedical world faces. Though many design factors and fabrication details must be considered, utilizing hydrogels as nitric oxide delivery vehicles provides promising materials in several applications. Such applications include cardiovascular therapy, vasodilation and angiogenesis, antimicrobial treatments, wound dressings, and stem cell research. Herein, a recent update on the progress of NO-releasing hydrogels is presented in depth. In addition, considerations for the design and fabrication of hydrogels and specific biomedical applications of nitric oxide-releasing hydrogels are discussed.
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