顺铂
免疫疗法
化疗
医学
癌症研究
药理学
内科学
癌症
作者
Tianzhu Ma,Liu‐Yi Liu,You‐Liang Zeng,Ke Ding,Hang Zhang,Wenting Liu,Qian Cao,Wei Xia,Xushen Xiong,Chao‐Liang Wu,Zong‐Wan Mao
出处
期刊:Chemical Science
[Royal Society of Chemistry]
日期:2024-01-01
卷期号:15 (25): 9756-9774
被引量:13
摘要
PyPDSplatins can not only bind G4s to repress c-MYC and VEGF expressions but also damage G4s to activate the immune-related cGAS-STING pathway and AIM2-ASC-related pyroptosis, triggering a strong immune response and potent antitumor effects.
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