WGCNA combined with machine learning to explore potential biomarkers and treatment strategies for acute liver failure, with experimental validation

We identified HORMAD2, WNT10A, ATP6V1E2, CMBL, ARRDC4, and LPIN2, as diagnostic biomarkers for ALF and demonstrated the effectiveness of eriodictyol for treating ALF. Immune cell infiltration may play a significant role in the pathogenesis and progression of ALF.