Wearable epidermal sensor patch with biomimetic microfluidic channels for fast and time-sequence monitoring of sweat glucose and lactate

Wearable sweat sensors enable non-invasive tracking and monitoring of human physiological information, which is expected to attract wide interest and rapid development in dietary health management and disease prevention. Unfortunately, sweat sensors are limited by rapid evaporation and low secretion rates of sweat. Herein, a sweat detection patch is proposed, which integrates bionic microchannels and multiparameter electrochemical sensors . The microfluidic channel (5°), which mimics ginkgo biloba veins, provided a 40 % higher flow rate compared to the normal channel (0°). Combined with burst pressure, the bionic channel enabled unidirectional transport of 6 μL sweat, effectively avoiding the mixing of old and new sweat. The electrochemical sensors possessed excellent specificity recognition, stability and durability, and have been used to detect substances in sweat, in particular to analyze changes in glucose concentration at different dietary intakes and changes in lactate metabolism after exercise. The rapid collection effect of the microchannels on trace sweat and the fast response of sensors have broad application prospects in real-time human health monitoring. • The biomimetic wedge-shaped patterned microchannels can rapidly transport 6 μL of sweat to the trace detection chamber. • Directional transfer of solution through bionic structural patches avoids mixing of old and new sweat. • Analysis of sweat glucose changes by electrochemical sensors under different dietary intakes for dietary health management.