微粒
药物输送
脂质体
纳米技术
药品
微球
患者依从性
毒品携带者
靶向给药
材料科学
药理学
生物医学工程
医学
化学工程
工程类
急诊医学
作者
Shital A. Kasture,Nilesh R. Bhosale,Ankita V. Bhosale,Pooja S . Gaurd,Pavan P. Kondewad
出处
期刊:International Journal for Research in Applied Science and Engineering Technology
[International Journal for Research in Applied Science and Engineering Technology (IJRASET)]
日期:2023-02-24
卷期号:11 (2): 1052-1062
标识
DOI:10.22214/ijraset.2023.49181
摘要
Abstract: Multiparticulate drug delivery methods frequently include microparticles, microspheres, and microcapsules, which have both medical and technological advantages. Microparticles are employed as multiunit drug delivery systems with welldefined physiological and pharmacokinetic benefits to increase efficacy, tolerance, and patient compliance. Their sizes range from 1 to 1000 m. In the creation of microparticles for drug delivery research, a variety of polymers have been used to increase therapeutic effectiveness while lowering side effects. Microparticles today are made of polymers, ceramic, and glass. Microparticles are more stable in the biological milieu than liposomes are. Surface-linked targeting moiety can be built into microparticles. In order to administer drugs to specific areas, this technique is employed. For controlled and long-term release, microparticles are also utilised. To treat many sick states such ophthalmic disorders, cancer, cardiac diseases, and inflammation, macromolecules are encapsulated inside microparticles. This review covers the pros, cons, types of microparticles, preparation method, evaluation of microparticles, and applications.
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