ผลลพธของการให surfactant ดวยวธ INSURE เทยบกบการให surfactant วธเดมในทารกเกดกอนกำหนดทมปญหา respiratory distress syndrome

Abstract            Objective: To analyze neonatal outcomes between INSURE method and conventional method for surfactant administration in preterm infants with respiratory distress syndrome (RDS).            Methods: A retrospective study was performed, including preterm infants with diagnosed RDS, who were admitted in NICU of Phatthalung hospital between 1st January 2017 and 31th December 2019. Surfactant administration with INSURE method (n=59) and conventional method (n=65), were performed.            Results: One-hundred and twenty-four infants were diagnosed with RDS. The mean birth weight and gestational age of infants were 1426  410 g and 30  2.7 weeks, respectively. The neonatal outcomes including ventilator day, oxygen day and length of hospital stay in INSURE group were significantly lower than conventional group.            Conclusion: Surfactant administration with INSURE method can improve neonatal outcome and suitable to as an alternative initial treatment for preterm infants with respiratory distress syndrome.   Keywords: respiratory distress syndrome, surfactant, INSURE