Marine Polysaccharides for Wound Dressings Application: An Overview

伤口敷料 自愈水凝胶 伤口愈合 多糖 生物相容性 化学 医学 材料科学 外科 复合材料 生物化学 有机化学
作者
Shenghai Shen,Xiaowen Chen,Zhewen Shen,Hao Chen
出处
期刊:Pharmaceutics [Multidisciplinary Digital Publishing Institute]
卷期号:13 (10): 1666-1666 被引量:75
标识
DOI:10.3390/pharmaceutics13101666
摘要

Wound dressings have become a crucial treatment for wound healing due to their convenience, low cost, and prolonged wound management. As cutting-edge biomaterials, marine polysaccharides are divided from most marine organisms. It possesses various bioactivities, which allowing them to be processed into various forms of wound dressings. Therefore, a comprehensive understanding of the application of marine polysaccharides in wound dressings is particularly important for the studies of wound therapy. In this review, we first introduce the wound healing process and describe the characteristics of modern commonly used dressings. Then, the properties of various marine polysaccharides and their application in wound dressing development are outlined. Finally, strategies for developing and enhancing marine polysaccharide wound dressings are described, and an outlook of these dressings is given. The diverse bioactivities of marine polysaccharides including antibacterial, anti-inflammatory, haemostatic properties, etc., providing excellent wound management and accelerate wound healing. Meanwhile, these biomaterials have higher biocompatibility and biodegradability compared to synthetic ones. On the other hand, marine polysaccharides can be combined with copolymers and active substances to prepare various forms of dressings. Among them, emerging types of dressings such as nanofibers, smart hydrogels and injectable hydrogels are at the research frontier of their development. Therefore, marine polysaccharides are essential materials in wound dressings fabrication and have a promising future.
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