核酸
分子信标
环介导等温扩增
核酸定量
核酸检测
DNA
计算生物学
计算机科学
聚合酶链反应
分子生物学
生物
生物化学
基因
寡核苷酸
作者
Ashley R. Connolly,Matt Trau
标识
DOI:10.1002/anie.200906992
摘要
Not bad at all: A simple biological circuit composed of two integrated molecular switches was developed for the detection and amplification of a specific nucleic acid in a biological extract. The nucleic acid is recognized by a molecular beacon, then a DNA polymerase and nicking endonuclease are used to rapidly amplify the signal for sensitive detection of the nucleic acid. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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