In Vitro Proliferation of Various Human Dental Stem Cells

To ascertain the properties of human dental stem cells, various postnatal human stem cells were isolated from extracted human teeth and jawbones. Isolated dental stem cells were plated until losing their ‘stemness’ and were evaluated for their proliferation rate, colony forming efficiency, and expression of a specific stem cell marker. These dental stem cells have the potential to proliferate for more than 10 passages, except for the maxillary bone marrow stem cells (MXBMSCs). In particular, stem cells obtained from the periapical follicle (PAFSCs) were definitely superior to the other dental stem cells in proliferation, colony forming efficiency and expression of specific stem cells marker.