Total flavonoids from Abrus cantoniensis alleviate fatty liver hemorrhagic syndrome in laying hens by regulating inflammation, oxidative stress, and cecal metabolites and microbiota

= 0.003) was inhibited. In conclusion, this study demonstrated that TFAC ameliorated FLHS through multiple mechanisms, including attenuating hepatic inflammation, enhancing antioxidant capacity, and modulating cecal metabolites and microbiota. These findings suggest the potential of TFAC as a feed additive for improving poultry liver health.