Risk stratification for isolated tricuspid valve surgery assisted using the Model for End-Stage Liver Disease score

医学 三尖瓣 肝病 内科学 终末期肝病模型 弗雷明翰风险评分 外科 人口 欧洲分数 心脏病学 心脏外科 疾病 肝移植 移植 环境卫生
作者
Gloria Färber,Jonas Marx,André Scherag,Ibrahim Saqer,Mahmoud Diab,Christoph Sponholz,Torsten Doenst
出处
期刊:The Journal of Thoracic and Cardiovascular Surgery [American Association for Thoracic Surgery]
卷期号:166 (5): 1433-1441.e1 被引量:11
标识
DOI:10.1016/j.jtcvs.2021.11.102
摘要

Isolated tricuspid valve surgery is perceived as high-risk. This perception is nurtured by patients who often present with substantial liver dysfunction, which is inappropriately reflected in current surgical risk scores (eg, the Society of Thoracic Surgeons [STS] score has no specific tricuspid model). The Model for End-Stage Liver Disease (MELD) has was developed as a measure for the severity of liver dysfunction. We report scores and outcomes for our patient population.We calculated STS, European System for Cardiac Operative Risk Evaluation (EuroSCORE) II (ESII), and MELD scores for all of our patients who received isolated tricuspid valve surgery between 2011 and 2020 (n = 157). We determined the MELD score, stratified patients into 3 groups (MELD <10: low, n = 53; 10 to <20: intermediate, n = 78; ≥20: high, n = 26) and describe associated outcomes.Patients were 72 ± 10 years old and 43% were male. Mean STS score was 4.9 ± 3.5% and ESII was 7.2 ± 6.6%. Mortality was 8.9% at 30 days and 65% at latest follow-up (95% CI, 51%-76%). Median follow-up was 4.4 years (range, 0-9.7 years). Although ESII and STS score accurately predicted 30-day mortality at low MELD scores (observed to expected [O/E] for ESII score = 0.8 and O/E for STS score = 1.0) and intermediate MELD (O/E for ESII score = 0.7, O/E for STS score = 1.0), mortality was underestimated at high MELD (O/E for ESII score = 3.0, O/E for STS score = 4.7). This subgroup also had higher incidence of new-onset hemodialysis. Besides MELD category, recent congestive heart failure, endocarditis, and hemodialysis were also associated with 30-day mortality.For isolated tricuspid valve regurgitation, classic surgical risk stratification with STS or ESII scores failed to predict perioperative mortality if there was evidence of severe liver dysfunction. Preoperative MELD assessment might be useful to assist in proper risk assessment for isolated tricuspid valve surgery.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
wy.he发布了新的文献求助10
1秒前
郭先森3316发布了新的文献求助10
1秒前
曹小仙男完成签到 ,获得积分10
3秒前
Gulu_完成签到 ,获得积分10
5秒前
5秒前
边小倩发布了新的文献求助10
9秒前
12秒前
大模型应助DoctorPeng采纳,获得10
17秒前
SciKid524发布了新的文献求助30
21秒前
科研通AI2S应助科研通管家采纳,获得10
22秒前
22秒前
李爱国应助科研通管家采纳,获得10
22秒前
23秒前
28秒前
要减肥百川完成签到,获得积分20
34秒前
adi完成签到,获得积分10
36秒前
田様应助小新爱看文献采纳,获得10
37秒前
徐伟康完成签到 ,获得积分10
37秒前
爆米花应助要减肥百川采纳,获得10
37秒前
shuijinhehuo完成签到,获得积分10
38秒前
shame完成签到 ,获得积分10
39秒前
田様应助WQ采纳,获得10
43秒前
完美世界应助Daybreak采纳,获得10
43秒前
菠萝谷波完成签到 ,获得积分10
44秒前
45秒前
skxxxxxx完成签到 ,获得积分10
46秒前
SciGPT应助Anthocyanidin采纳,获得30
47秒前
Jasper应助ppat5012采纳,获得10
51秒前
魏凌飞完成签到,获得积分10
51秒前
51秒前
小马甲应助欢喜紫安采纳,获得10
54秒前
一二三四完成签到,获得积分10
1分钟前
1分钟前
1分钟前
1分钟前
今后应助拼搏的乐双采纳,获得10
1分钟前
杨璐骏发布了新的文献求助10
1分钟前
1分钟前
ppat5012发布了新的文献求助10
1分钟前
LLL完成签到,获得积分10
1分钟前
高分求助中
Manual of Clinical Microbiology, 4 Volume Set (ASM Books) 13th Edition 1000
Teaching Social and Emotional Learning in Physical Education 900
The three stars each : the Astrolabes and related texts 550
Boris Pesce - Gli impiegati della Fiat dal 1955 al 1999 un percorso nella memoria 500
Chinese-English Translation Lexicon Version 3.0 500
Recherches Ethnographiques sue les Yao dans la Chine du Sud 500
Two-sample Mendelian randomization analysis reveals causal relationships between blood lipids and venous thromboembolism 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 有机化学 工程类 生物化学 纳米技术 物理 内科学 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 电极 光电子学 量子力学
热门帖子
关注 科研通微信公众号,转发送积分 2398928
求助须知:如何正确求助?哪些是违规求助? 2099906
关于积分的说明 5293858
捐赠科研通 1827590
什么是DOI,文献DOI怎么找? 911015
版权声明 560061
科研通“疑难数据库(出版商)”最低求助积分说明 486928