分级(工程)
病态的
病理
医学
纤维腺瘤
叶状瘤
乳腺癌
生物
内科学
癌症
生态学
作者
Dominique Yuan Bin Seow,Timothy Kwang Yong Tay,Puay Hoon Tan
标识
DOI:10.1053/j.semdp.2022.04.001
摘要
Breast fibroepithelial lesions, which are composed of biphasic epithelial and stromal proliferations, comprise the fascinating spectrum of fibroadenomas and phyllodes tumours. Common difficulties surrounding their diagnosis include distinguishing between cellular fibroadenomas and benign phyllodes tumours, grading phyllodes tumours, classifying fibroepithelial lesions in paediatric patients, and handling surgical margins. Recent molecular advances have provided insights into the pathogenesis of fibroepithelial lesions and may offer diagnostic, prognostic, and therapeutic information. In this review, we briefly revisit the pathological features of fibroadenomas and phyllodes tumours, discuss common diagnostic dilemmas and management implications, and examine their key molecular characteristics.
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