生物
泛素
Wnt信号通路
核糖核酸
分子生物学
异位表达
癌症研究
细胞生物学
细胞培养
信号转导
基因
生物化学
遗传学
作者
Zheng Wang,Anqi Sun,Aihui Yan,Jian Yao,Haibo Huang,Ziming Gao,Tao Han,Jia Gu,Ni Li,Huizhe Wu,Kai Li
标识
DOI:10.1186/s12943-022-01570-4
摘要
Our findings manifested a novel circMTCL1-C1QBP-β-catenin signaling axis involving in LSCC tumorigenesis and progression, which shed new light on circRNAs-ubiquitous acidic glycoprotein mediated ubiquitin degradation and provided strategies and targets in the therapeutic intervention of LSCC.
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