医学
他达拉非
安慰剂
内科学
cGMP特异性磷酸二酯酶5型
糖尿病
心脏病学
内分泌学
西地那非
病理
替代医学
作者
Riccardo Pofi,Elisa Giannetta,Tiziana Feola,Nicola Galea,Federica Barbagallo,Federica Campolo,Roberto Badagliacca,Biagio Barbano,Federica Ciolina,Giuseppe Defeudis,Tiziana Filardi,Franz Sesti,Marianna Minnetti,Carmine Dario Vizza,Patrizio Pasqualetti,Pierluigi Caboni,Iacopo Carbone,Marco Francone,Carlo Catalano,Paolo Pozzilli
标识
DOI：10.1126/scitranslmed.abl8503
摘要
monocytes increased. Nine patients (14.5%) had minor adverse reactions after tadalafil administration. Continuous PDE5 inhibition could offer a strategy to target cardiorenal complications of T2DM, with sex- and tissue-specific responses. Further studies are needed to confirm Klotho and hsa-miR-199-5p as markers for T2DM complications.
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(2025-6-4)
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