医学
癌症
心肌病
心脏功能不全
心力衰竭
重症监护医学
心脏病学
内科学
心肌纤维化
肿瘤科
作者
Efstratios Koutroumpakis,Nikhil Agrawal,Nicolas Palaskas,Jun‐ichi Abe,Cezar Iliescu,Syed Wamique Yusuf,Anita Deswal
标识
DOI:10.1016/j.hfc.2022.02.011
摘要
Myocardial dysfunction in patients with cancer is a major cause of morbidity and mortality. Cancer therapy-related cardiotoxicities are an important contributor to the development of cardiomyopathy in this patient population. Furthermore, cardiac AL amyloidosis, cardiac malignancies/metastases, accelerated atherosclerosis, stress cardiomyopathy, systemic and pulmonary hypertension are also linked to the development of myocardial dysfunction. Herein, we summarize current knowledge on the mechanisms of myocardial dysfunction in the setting of cancer and cancer-related therapies. Additionally, we briefly outline key recommendations on the surveillance and management of cancer therapy-related myocardial dysfunction based on the consensus of experts in the field of cardio-oncology.
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