Introduction: rationality in an uncertain practice PART 1: MEDICINE AS A PRACTICE 1. Medicine and the limits of knowledge 2. The misdescription of medicine 3. Clinical judgement and the interpretation of case PART 2: CLINICAL JUDGEMENT AND THE IDEA OF CAUSE 4. What brings you here today?: the idea of cause in medical practice 5. The simplification of clinical cause 6. Clinical judgement and the problem of particularizing PART 3: THE FORMATION OF CLINICAL JUDGEMENT 7. Aphorisms, maxims, and old saws: some rules of clinical reasoning 8. Don't think zebras: a theory of clinical knowing 9. Knowing one's place: the evaluation of clinical judgement PART 4: CLINICAL JUDGEMENT AND THE NATURE OF MEDICINE 10. The self in medicine: the use and misuse of the science claim 11. A medicine of neighbours 12. Uncertainty and the ethics of practice