Straightforward synthesis of functionalized chroman-4-ones through cascade radical cyclization-coupling of 2-(allyloxy)arylaldehydes

A novel and direct approach to synthesize a series of phosphonate, azide and hydroxy functionalized chroman-4-ones has been developed. The transformation appears to proceedviaan intramolecular addition ofin situgenerated acyl radical onto alkene, followed by a radical/radical cross coupling.