内膜增生
血管平滑肌
抑制性突触后电位
医学
肽
平滑肌
细胞生物学
化学
增生
内科学
生物
生物化学
作者
Brian C. Evans,Kyle M. Hocking,Michael J. Osgood,Igor Voskresensky,Julia Dmowska,Kameron V. Kilchrist,Colleen M. Brophy,Craig L. Duvall
标识
DOI:10.1126/scitranslmed.aaa4549
摘要
Nanopolyplexes formulated from a pH-responsive, endosomolytic polymer with a peptide inhibitor of MAPKAP kinase 2 block inflammatory and migratory signaling in vascular smooth muscle cells and prevent intimal hyperplasia in human saphenous vein grafts.
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