Rodent Model for High Altitude and Ebullism Exposure Studies

This initial study highlights the different pathophysiological regimes that exist beyond Armstrong's line and subdivides ebullism exposures into two different classes, which can be operationally associated with cabin vs. suit depressurization events. These are now presented as Type A Complex Ebullism and Type B Simple Ebullism. The former is characterized by a combination of barotrauma, hypoxia, ebullism, and decompression sickness, while the latter presents as only ebullism. Garbino A, Nusbaum D, Goughnour S, Dalal S, Carminati M-VG, Clark J. Rodent model for high altitude and ebullism exposure studies. Aerosp Med Hum Perform. 2025; 96(3):198-205.