Conduction system pacing compared with biventricular pacing for cardiac resynchronization therapy in patients with heart failure and mildly reduced left ventricular ejection fraction: Results from International Collaborative LBBAP Study (I-CLAS) Group

Cardiac resynchronization therapy is a guideline-recommended therapy in patients with heart failure, mildly reduced left ventricular ejection fraction (HFmrEF 36-50%), and left bundle branch block or indication for ventricular pacing. Conduction system pacing (CSP) utilizing left bundle branch area pacing (LBBAP) or His bundle pacing (HBP) has been shown to be a safe and physiologic alternative to biventricular pacing (BVP).