科学网
文献计量学
免疫系统
中国
图书馆学
骨质疏松症
骨重建
斯科普斯
医学
地理
政治学
梅德林
计算机科学
内科学
免疫学
荟萃分析
考古
法学
作者
Jinlong Zhao,Yaoxing Dou,Guihong Liang,Haozhang Huang,Kunhao Hong,Weiyi Yang,Guanghui Zhou,Baoyong Sha,Jun Li,Lingfeng Zeng
出处
期刊:Endocrine, metabolic & immune disorders
[Bentham Science]
日期:2023-10-20
卷期号:23
被引量:1
标识
DOI:10.2174/0118715303257269231011073100
摘要
Osteoporosis (OP) is a systemic bone metabolism disorder in which the immune system and bone metabolism interact.The purpose of this study was to explore the research status, hot spots and trends regarding the influence of the immune system on OP and to provide a basis for research directions and applications in this field.We searched and collected literature about the immune system and OP published from 2012 to 2022 in the Web of Science Core Collection database. All the included studies were subjected to bibliometrics analysis using Hiplot Pro, VOSviewer and CiteSpace software to produce statistics and visual analyses of the literature output, countries, institutions, authors, keywords and journals.A total of 1201 papers were included, and the number of citations of these articles reached 31,776. The number of publications and citations on the immune system and OP has increased year by year. The top three countries with the greatest number of papers published were China, the United States of America (USA) and Italy. The two institutions with the largest number of papers published were Sichuan University and Soochow University, both located in China. De Martinis Massimo (Italy) and Ginaldi Lia (Italy) are prolific authors in this field. The representative academic journals are Osteoporosis International, Frontiers in Immunology, Journal of Bone and Mineral Research, PloS One and Bone. The results of the keyword cooccurrence analysis showed that the research topics in this field mainly focused on T cells, cytokines, signaling pathways, vitamin D, postmenopausal OP and immune diseases. The keyword burst results showed that zoledronic acid, chain fatty acids and gut microbiota are the frontiers and trends of future research on this topic.The influence of the immune system on OP has been widely studied, and the current research in this field focuses on the effect or mechanism of immune-related cytokines, signaling pathways and vitamin D on OP. Future research trends in this field should focus on the immune regulation mechanism and clinical transformation of zoledronic acid, chain fatty acids and the gut microbiota in OP.
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