Obstructive sleep apnea risk factor for chronic kidney disease: A systematic review and meta-analysis

Introduction: Obstructive sleep apnea (OSA) is related to chronic kidney disease (CKD), but its association is not fully understood. Objective: To realize a systematic review with meta-analysis to determine the association between OSA and CKD. Methods: Systematic review with meta-analysis of observational studies. The search was carried out in Embase, PubMed/Medline, Scopus, and Web of Science. The data were calculated by the hazard ratio (HR). The heterogeneity was identified by I squared. Results: Five studies were included (n=6,710). The meta-analysis found an association between OSA and CKD (HR=2.00; confidence interval 95%=1.68-2.38). Conclusions: We found an association between OSA and CKD.