Adult ileocolic intussusception due to primary diffuse large B-cell lymphoma

Intestinal intussusception is an uncommon condition in adults. Unlike the idiopathic spontaneous occurrence in children, about half of the cases in this population are associated with malignant neoplasms. This report describes a 44-year-old male patient presenting with abdominal pain and signs of intestinal obstruction. Through a CT examination, the patient was diagnosed with ileocecal intussusception. A 3 cm lesion was found in the terminal ileum, and a segmental enterectomy was performed. An immunohistochemical analysis identified a large B-cell lymphoma. Due to the high association with tumors, the finding of intestinal intussusception in adults should be properly investigated, regardless of symptoms.