A case report of vitiligo following toripalimab therapy for a patient with metastatic melanoma

Figure S1. Immunohistochemistry for pathological examination. Immunohistochemistry showing malignant cells immunoreactive for MB-45, original magnification: (a) 10×, (b) 20×. Immunoreactive for HMB-45, original magnification: (d) 10×, (e) 20×. Immunoreactive for S-100, original agnification: (c)10×, (f) 20×. Figure S2. Histopathological features of malignant melanoma. The tumor cells are large, round, and diffused in sheets and nests, with visible nucleoli, thick chromatin granules, and abundant eosinophilic cytoplasm; melanin granules can be seen in the cytoplasm. Original magnification: (a) 4×, (b) 10×, (c) 20×, (d) 40×. Figure S3. Representative dermoscopic image from a vitiligo lesion. Figure S4. Photograph taken under Wood's lamp. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.