Advances in Genomic Data and Biomarkers: Revolutionizing NSCLC Diagnosis and Treatment

精密医学 个性化医疗 医学 生物标志物 生物标志物发现 肺癌 数据科学 生物信息学 重症监护医学 计算机科学 肿瘤科 病理 蛋白质组学 生物 生物化学 基因
作者
Juan Carlos Restrepo,Diana Dueñas,Zuray Corredor,Yamil Liscano
出处
期刊:Cancers [Multidisciplinary Digital Publishing Institute]
卷期号:15 (13): 3474-3474
标识
DOI:10.3390/cancers15133474
摘要

Non-small cell lung cancer (NSCLC) is a significant public health concern with high mortality rates. Recent advancements in genomic data, bioinformatics tools, and the utilization of biomarkers have improved the possibilities for early diagnosis, effective treatment, and follow-up in NSCLC. Biomarkers play a crucial role in precision medicine by providing measurable indicators of disease characteristics, enabling tailored treatment strategies. The integration of big data and artificial intelligence (AI) further enhances the potential for personalized medicine through advanced biomarker analysis. However, challenges remain in the impact of new biomarkers on mortality and treatment efficacy due to limited evidence. Data analysis, interpretation, and the adoption of precision medicine approaches in clinical practice pose additional challenges and emphasize the integration of biomarkers with advanced technologies such as genomic data analysis and artificial intelligence (AI), which enhance the potential of precision medicine in NSCLC. Despite these obstacles, the integration of biomarkers into precision medicine has shown promising results in NSCLC, improving patient outcomes and enabling targeted therapies. Continued research and advancements in biomarker discovery, utilization, and evidence generation are necessary to overcome these challenges and further enhance the efficacy of precision medicine. Addressing these obstacles will contribute to the continued improvement of patient outcomes in non-small cell lung cancer.
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